Nadis are the Channels through which Prana of the physical body, the subtle body and casual body are said to flow. With-in this physical framework, the nadis are said to connect at special points of intensity, the chakras. The three principal nadis run from the base of the spine to the top of head and are the Ida on the left, the Pingla on the right and Sushumna in the centre.
The nadis play a role in yoga as many yogic practices including Shaktkarma, mudras and pranayama are intended to open and unblock the nadis. The ultimate aim of some yogic practices is to direct prana into Sushumna nadi specifically enabling kundalini to rise and thus bring about moksha or liberation.

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